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Distinguishing SNPs from Sequencing Errors
Variant-analysis is an important question. How do we know whether a SNP is real or due to sequencing error?
In this section, we consider a biological problem from a recent paper and show how it can be solved by R, C, C++ and … The choice of the problem is arbitrary. We tried to make sure it is not one of the problems we are working on so that we have the same barrier as anyone else in solving it. The problem is also potentially interesting. Thirdly, it uses NGS. Fourthly, supplementary section has lot of details.
