Alchemy simulator included along with BLASR package from PacBio.
<A href=http://www.ncbi.nlm.nih.gov/pubmed/23129296>A paper by Y. Ono et al.</A> reported developing a simulator for PacBio reads. The simulator PBSIM is publicly available from google repository (<A href=http://code.google.com/p/pbsim/>http://code.google.com/p/pbsim/</A>) under the GNU GPL v2 license.