We are back after making extensive changes to the blog software being used here.
Most important among the changes, we got rid of Wordpress and made a commitment to
never use Wordpress again. Wordpress is easy to install, but nightmare to maintain
with its entire panoply of buggy plugins. Moreover, it sucks up time by failing at the
most unfortunate times.
Lynn Yi, Harlod Pimentel and Lior Pachter published a new
RNAseq paper that our
readers will definitely find interesting. In this paper, the authors showcase the
new RNAseq technologies Pachterlab has been developing over the last few years. We
covered those components (e.g Kallisto, Sleuth) in earlier posts, but here you can
see a biological application to get new insights from already published data.
Readers may keep an eye on #SMRTBFX hashtag on twitter to follow an ongoing conference. This is the best place to know about the latest bioinformatics algorithms on long reads.
Gene Myers is again the star of the show. He has been distributing a lot of goodies through his Dazzlerblog, such as -
A large number of NIH-funded parasites waste taxpayers’
money with the excuse that they are working
toward improving the health of Americans. Francis Collins, the head of NIH,
uses every opportunity to tell everyone how research funded by NIH helps in
improving the life expectancy of Americans (a flat out lie). Yet, when
research by Deaton and Case uncovered that the life expectancy of Americans of
prime age (45-54) was falling, primarily due to rising suicides, Collins and
his minions went completely silent.
‘Ancient’ Bene Israel Jews and late-arrived Baghdadi Jews in India started the
Bollywood movie industry. Many famous early Indian actresses also came from
these communities. This is not common knowledge in India, because those
actresses took Muslim (Firoza Begum) or Hindu (Sulochana, Pramila) screen
In 2013, Dr. Elhaik complained about his home page at John Hopkins University
mysteriously disappearing from google searches right after his first Jewish
genomics paper started to gain
attention. We reproduced his complaint here, and then his page came back on
top again after a few days.
Among all biomolecules within the cell, tRNAs got the least respect. Their
supposed importance ended right after the ‘adaptors’ related to entries in the
genetic code table were identified (mid-60s). Since then, the attention
shifted to more complex RNAs like the rRNAs.
Among various biotechnology inventions of the last few years with potential to
revolutionize medicine, nothing excites us more than growing of three-
dimensional human organoids on matrigel. Therefore, we plan to devote a number
of posts on this topic to keep our readers aware of the practices, potentials
Our earlier article on Illumina’s surprise
announcement received a number of informative comments. We
like to discuss them here, but first it is important to explain the term ‘peak
sequencing’ properly. That explanation requires us to discuss the relevance of
using Moore’s law for sequencing.